Effect of configuration of muramyl dipeptide glycoside bond and structure of glypside aglycon on their capacity to stimulate production of interleukin-1 and tumor necrosis factor by macrophages

被引：3

作者：

Kalyuzhin, OV ^{[1
]}

Nelyubov, MV ^{[1
]}

Kalyuzhina, EV ^{[1
]}

Kuzovlev, FN ^{[1
]}

Shkalev, MV ^{[1
]}

机构：

[1] Russian Acad Med Sci, Inst Human Morphol, Lab Cell Immunopathol & Biotechnol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2002年 / 134卷 / 03期

关键词：

muramyl dipeptide glycosides; interleukin-1; tumor necrosis factor;

D O I：

10.1023/A:1021519921125

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Effects of 11 original glycoside derivatives of muramyl dipeptide on the production of interleukin-1 and tumor necrosis factor by mouse peritoneal macrophages were studied. The relationship between macrophage activation evaluated by induction of these cytokines and configuration of glycoside bond and aglycon structure of MDP was revealed.

引用

页码：281 / 283

页数：3