Thyroid hormones and treatment of obesity

被引:51
作者
Krotkiewski, M [1 ]
机构
[1] Sahlgrens Childrens Hosp, Dept Rehabil Med, Gothenburg, Sweden
关键词
thyroid hormones; obesity; diiodothyronine; UCP;
D O I
10.1038/sj.ijo.0801294
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Thyroid hormones have important thermogenic function. Nevertheless, thyroid dysfunctions are often associated with minor changes in body weight and fat mass. On the other hand, both overfeeding and fasting have important effects on iodothyronine metabolism and regulation of deiodinase activity. Although under debate, there are clinical and theoretical reasons to administer low-dose thyroid hormones (T3) in selected obese patients. This short review deals with both pathophysiological and clinical aspects of thyroid hormone used in the therapy of obesity.
引用
收藏
页码:S116 / S119
页数:4
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