Sex differences in semantic language processing: A functional MRI study

被引：104

作者：

Baxter, LC

Saykin, AJ

Flashman, LA

Johnson, SC

Guerin, SJ

Babcock, DR

Wishart, HA

机构：

[1] Dartmouth Coll Sch Med, DHMC, Dept Psychiat, Brain Imaging Lab, Lebanon, NH 03756 USA

[2] Barrow Neurol Inst, Phoenix, AZ 85013 USA

[3] Dartmouth Coll Sch Med, Dept Radiol, Lebanon, NH 03756 USA

[4] New Hampshire Hosp, Concord, NH 03301 USA

来源：

BRAIN AND LANGUAGE | 2003年 / 84卷 / 02期

关键词：

sex differences; language; lateralization; functional MRI; semantic memory;

D O I：

10.1016/S0093-934X(02)00549-7

中图分类号：

R36 [病理学]; R76 [耳鼻咽喉科学];

学科分类号：

100104 ; 100213 ;

摘要：

Predictions based on two models of sex differences in cerebral organization of language were compared by examining fMRI patterns of 10 females and 9 males during a semantic processing task. Both groups displayed activation of left inferior frontal gyrus (IFG), left superior temporal gyrus (STG), and cingulate. Females, but not males, showed bilateral IFG and STG activation. Further analyses revealed females had less diffuse left activation and greater right posterior temporal and insula region activation than males. Results support both an interhemispheric and an intrahemispheric model of sex differences in language, suggesting that the models may not be mutually exclusive. (C) 2002 Elsevier Science (USA). All rights reserved.

引用

页码：264 / 272

页数：9

共 30 条

[21] Neuroanatomic substrates of semantic memory impairment in Alzheimer's disease: Patterns of functional MRI activation [J].