Electro-oxidative kinetic resolution of sec-alcohols by using an optically active N-oxyl mediator

被引：58

作者：

Kuroboshi, M ^{[1
]}

Yoshihisa, H ^{[1
]}

Cortona, MN ^{[1
]}

Kawakami, Y ^{[1
]}

Gao, Z ^{[1
]}

Tanaka, H ^{[1
]}

机构：

[1] Okayama Univ, Fac Engn, Dept Appl Chem, Okayama 7008530, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 42期

关键词：

kinetic resolution; electrochemistry; oxidation; alcohols;

D O I：

10.1016/S0040-4039(00)01419-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Electro-oxidative kinetic resolution of sec-alcohols mediated with a catalytic amount of an optically active N-oxyl was performed by use of a simple undivided cell under constant current conditions. The selectivity factor (S-value) increased remarkably when the reaction was performed at lower temperatures. The optically active N-oxyl was recovered and used repeatedly without any change in efficiency and selectivity. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8131 / 8135

页数：5