Combinatorial generation of nucleobase libraries by MCR

被引:9
作者
Domling, A
Richter, W
Ugi, I
机构
[1] MORPHOCHEM GES KOMBINATOR CHEM MBH,D-81476 MUNICH,GERMANY
[2] TECH UNIV MUNICH,INST ORGAN CHEM & BIOCHEM,D-85747 GARCHING,GERMANY
来源
NUCLEOSIDES & NUCLEOTIDES | 1997年 / 16卷 / 7-9期
关键词
D O I
10.1080/07328319708006270
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Multi component reactions (MCR) together with a suitable set of nucleobase building blocks provide a valuable tool for the fast generation of combinatorial libraries. These arrays of compounds are of high interest as anticancer and antiviral drugs. The preparation of small libraries and their analytics is described.
引用
收藏
页码:1753 / 1756
页数:4
相关论文
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