Recognition of Patterned Molecular Ink with Phage Displayed Peptides

被引:24
作者
Cui, Yue [1 ]
Pattabiraman, Anupama [1 ]
Lisko, Bozhena [1 ]
Collins, Samantha C. [1 ]
McAlpine, Michael C. [1 ]
机构
[1] Princeton Univ, Dept Mech & Aerosp Engn, Princeton, NJ 08544 USA
关键词
NANOWIRES;
D O I
10.1021/ja9081809
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The development of a reliable method for patterning and recognizing molecular inks could enable exciting avenues in fundamental research and novel applications. Phage display is a powerful method for identifying peptides that possess enhanced selectivity and binding affinity toward a variety of targets. Here, we demonstrate for the first time the immobilization and recognition of a small molecular ink with screened phage displayed peptides. Our approach is based on a unique mix of comprehensive phage displayed peptide screening processes, along with novel micropatterning techniques. These results, combined with the large variety of available inks and surface chemistries, Could open up opportunities in cell biology, nanomaterials self-assembly, selective sensors, and even energy storage applications.
引用
收藏
页码:1204 / +
页数:4
相关论文
共 16 条
[1]   Microcontact printing of indium metal using salt solution "ink" [J].
Allen, C. G. ;
Dorr, J. C. ;
Khandekar, A. A. ;
Beach, J. D. ;
Schick, I. C. ;
Schick, E. J. ;
Collins, R. T. ;
Kuech, T. F. .
THIN SOLID FILMS, 2007, 515 (17) :6812-6816
[2]   Directed assembly of one-dimensional nanostructures into functional networks [J].
Huang, Y ;
Duan, XF ;
Wei, QQ ;
Lieber, CM .
SCIENCE, 2001, 291 (5504) :630-633
[3]   Evolutionary screening of biomimetic coatings for selective detection of explosives [J].
Jaworski, Justyn W. ;
Raorane, Digvijay ;
Huh, Jin H. ;
Majumdar, Arunava ;
Lee, Seung-Wuk .
LANGMUIR, 2008, 24 (09) :4938-4943
[4]   Virus-based toolkit for the directed synthesis of magnetic and semiconducting nanowires [J].
Mao, CB ;
Solis, DJ ;
Reiss, BD ;
Kottmann, ST ;
Sweeney, RY ;
Hayhurst, A ;
Georgiou, G ;
Iverson, B ;
Belcher, AM .
SCIENCE, 2004, 303 (5655) :213-217
[5]   Peptide-nanowire hybrid materials for selective sensing of small molecules [J].
McAlpine, Michael C. ;
Agnew, Heather D. ;
Rohde, Rosemary D. ;
Blanco, Mario ;
Ahmad, Habib ;
Stuparu, Andreea D. ;
Goddard, William A., III ;
Heath, James R. .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (29) :9583-9589
[6]   Patterning of functional antibodies and other proteins by photolithography of silane monolayers [J].
Mooney, JF ;
Hunt, AJ ;
McIntosh, JR ;
Liberko, CA ;
Walba, DM ;
Rogers, CT .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (22) :12287-12291
[7]   Biomimetic synthesis and patterning of silver nanoparticles [J].
Naik, RR ;
Stringer, SJ ;
Agarwal, G ;
Jones, SE ;
Stone, MO .
NATURE MATERIALS, 2002, 1 (03) :169-172
[8]   Virus-enabled synthesis and assembly of nanowires for lithium ion battery electrodes [J].
Nam, KT ;
Kim, DW ;
Yoo, PJ ;
Chiang, CY ;
Meethong, N ;
Hammond, PT ;
Chiang, YM ;
Belcher, AM .
SCIENCE, 2006, 312 (5775) :885-888
[9]   Epoxy-silane linking of biomolecules is simple and effective for patterning neuronal cultures [J].
Nam, Yoonkey ;
Branch, Darren W. ;
Wheeler, Bruce C. .
BIOSENSORS & BIOELECTRONICS, 2006, 22 (05) :589-597
[10]   Peptide-mediated formation of single-wall carbon nanotube composites [J].
Pender, MJ ;
Sowards, LA ;
Hartgerink, JD ;
Stone, MO ;
Naik, RR .
NANO LETTERS, 2006, 6 (01) :40-44