Kinetic control in noncovalent synthesis: Regioselective ligand exchange into a hydrogen bonded assembly

被引：17

作者：

Davis, JT ^{[1
]}

Kaucher, MS ^{[1
]}

Kotch, FW ^{[1
]}

Iezzi, MA ^{[1
]}

Clover, BC ^{[1
]}

Mullaugh, KM ^{[1
]}

机构：

[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 23期

关键词：

D O I：

10.1021/ol0483089

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This paper illustrates the use of a kinetically controlled exchange reaction to effect regioselective modification of a hydrogen-bonded assembly. Both the bound anion and cation can control the exchange of ligand into the different layers of a synthetic G-quadruplex.

引用

页码：4265 / 4268

页数：4

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