MULTIDRUG-RESISTANT ENTEROCOCCUS FAECIUM MENINGITIS IN A TODDLER CHARACTERIZATION OF THE ORGANISM AND SUCCESSFUL TREATMENT WITH INTRAVENTRICULAR DAPTOMYCIN AND INTRAVENOUS TIGECYCLINE

被引：55

作者：

Jaspan, Heather B. ^{[1
,2
]}

Brothers, Adam W. ^{[1
]}

Campbell, Angela J. P. ^{[1
,2
,3
]}

McGuire, John K. ^{[1
,2
]}

Browd, Samuel R. ^{[4
]}

Manley, Thomas J. ^{[1
,3
]}

Pak, Daniel ^{[2
]}

Weissman, Scott J. ^{[1
,2
]}

机构：

[1] Seattle Childrens Hosp, Dept Pediat, Seattle, WA 98105 USA

[2] Univ Washington, Dept Pediat, Seattle, WA 98195 USA

[3] Fred Hutchinson Canc Res Inst, Seattle, WA USA

[4] Seattle Childrens Hosp, Dept Neurol Surg, Seattle, WA USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2010年 / 29卷 / 04期

关键词：

vancomycin-resistant Enterococcus; tigecycline; daptomycin; meningitis; children; DAPTOMYCIN; VANCOMYCIN; VENTRICULITIS;

D O I：

10.1097/INF.0b013e3181c806d8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A case of enterococcal meningitis in a toddler is presented. The organism was highly resistant to all drugs previously used for pediatric Gram-positive meningitis. She was successfully treated with intraventricular and intravenous daptomycin and intravenous tigecycline. The organism was characterized as a member of CC17, a notorious emerging nosocomial clone of Enterococcus faecium.

引用

页码：379 / 381

页数：3

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