Resistive-pulse sensing - From microbes to molecules

被引:437
作者
Bayley, H
Martin, CR [1 ]
机构
[1] Univ Florida, Dept Chem, Gainesville, FL 32605 USA
[2] Univ Florida, Ctr Res Bio Nano Interface, Gainesville, FL 32605 USA
[3] Texas A&M Univ, Dept Med Biochem & Genet, Ctr Hlth Sci, College Stn, TX 77843 USA
[4] Texas A&M Univ, Dept Chem, College Stn, TX 77843 USA
关键词
D O I
10.1021/cr980099g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A review is made, with the aim of unifying various apparently disparate sensing strategies. The unifying feature is the underlying measurement principle that entails occlusion of an aperture through which a current is passing by the analyte species. The review focuses on two very recent manifestations of this sensing paradigm: the use of protein-based channels and nanotube membranes for small molecule and ion sensing.
引用
收藏
页码:2575 / 2594
页数:20
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