Resistive-pulse sensing - From microbes to molecules

被引:437
作者
Bayley, H
Martin, CR [1 ]
机构
[1] Univ Florida, Dept Chem, Gainesville, FL 32605 USA
[2] Univ Florida, Ctr Res Bio Nano Interface, Gainesville, FL 32605 USA
[3] Texas A&M Univ, Dept Med Biochem & Genet, Ctr Hlth Sci, College Stn, TX 77843 USA
[4] Texas A&M Univ, Dept Chem, College Stn, TX 77843 USA
关键词
D O I
10.1021/cr980099g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A review is made, with the aim of unifying various apparently disparate sensing strategies. The unifying feature is the underlying measurement principle that entails occlusion of an aperture through which a current is passing by the analyte species. The review focuses on two very recent manifestations of this sensing paradigm: the use of protein-based channels and nanotube membranes for small molecule and ion sensing.
引用
收藏
页码:2575 / 2594
页数:20
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共 173 条
[41]  
DINGLEDINE R, 1999, PHARM REV, V51
[42]   The design of protein-based catalysts using semisynthetic methods [J].
Distefano, MD ;
Kuang, H ;
Qi, DF ;
Mazhary, A .
CURRENT OPINION IN STRUCTURAL BIOLOGY, 1998, 8 (04) :459-465
[43]   The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].
Doyle, DA ;
Cabral, JM ;
Pfuetzner, RA ;
Kuo, AL ;
Gulbis, JM ;
Cohen, SL ;
Chait, BT ;
MacKinnon, R .
SCIENCE, 1998, 280 (5360) :69-77
[44]   Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway [J].
Dutzler, R ;
Wang, YF ;
Rizkallah, PJ ;
Rosenbusch, JP ;
Schirmer, T .
STRUCTURE, 1996, 4 (02) :127-134
[45]   Engineering of metal-ion sites as distance constraints in structural and functional analysis of 7TM receptors [J].
Elling, CE ;
Thirstrup, K ;
Nielsen, SM ;
Hjorth, SA ;
Schwartz, TW .
FOLDING & DESIGN, 1997, 2 (04) :S76-S80
[46]   CONVERSION OF ANTAGONIST-BINDING SITE TO METAL-ION SITE IN THE TACHYKININ NK-1 RECEPTOR [J].
ELLING, CE ;
NIELSEN, SM ;
SCHWARTZ, TW .
NATURE, 1995, 374 (6517) :74-77
[47]   Backbone mutations in transmembrane domains of a ligand-gated ion channel: Implications for the mechanism of gating [J].
England, PM ;
Zhang, YN ;
Dougherty, DA ;
Lester, HA .
CELL, 1999, 96 (01) :89-98
[48]   Site-specific, photochemical proteolysis applied to ion channels in vivo [J].
England, PM ;
Lester, HA ;
Davidson, N ;
Dougherty, DA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (20) :11025-11030
[49]   Siderophore-mediated iron transport: Crystal structure of FhuA with bound lipopolysaccharide [J].
Ferguson, AD ;
Hofmann, E ;
Coulton, JW ;
Diederichs, K ;
Welte, W .
SCIENCE, 1998, 282 (5397) :2215-2220
[50]   Biosensors in chemical separations [J].
Fishman, HA ;
Greenwald, DR ;
Zare, RN .
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 1998, 27 :165-198