Ciliogenesis: Polarity proteins on the move

被引:7
作者
Bossinger, O [1 ]
Bachmann, A [1 ]
机构
[1] Univ Dusseldorf, Inst Genet, D-40225 Dusseldorf, Germany
关键词
D O I
10.1016/j.cub.2004.09.039
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The formation and maintenance of cilia and flagella require a selective and directed transport along the axoneme, a characteristic central bundle of microtubules. Recent evidence suggests an interesting link between the generation of cilia and the protein complexes that establish apico-basal cell polarity.
引用
收藏
页码:R844 / R846
页数:3
相关论文
共 20 条
[1]   Decoding cilia function: Defining specialized genes required for compartmentalized cilia biogenesis [J].
Avidor-Reiss, T ;
Maer, AM ;
Koundakjian, E ;
Polyanovsky, A ;
Keil, T ;
Subramaniam, S ;
Zuker, CS .
CELL, 2004, 117 (04) :527-539
[2]   ERM proteins and merlin: Integrators at the cell cortex [J].
Bretscher, A ;
Edwards, K ;
Fehon, RG .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (08) :586-599
[3]   The intraflagellar transport machinery of Chlamydomonas reinhardtii [J].
Cole, DG .
TRAFFIC, 2003, 4 (07) :435-442
[4]  
Collet J, 1998, GENETICS, V148, P187
[5]   Localization of intraflagellar transport protein IFT52 identifies basal body transitional fibers as the docking site for IFT particles [J].
Deane, JA ;
Cole, DG ;
Seeley, ES ;
Diener, DR ;
Rosenbaum, JL .
CURRENT BIOLOGY, 2001, 11 (20) :1586-1590
[6]   Polarity proteins control ciliogenesis via kinesin motor interactions [J].
Fan, SL ;
Hurd, TW ;
Liu, CJ ;
Straight, SW ;
Weimbs, T ;
Hurd, EA ;
Domino, SE ;
Margolis, B .
CURRENT BIOLOGY, 2004, 14 (16) :1451-1461
[7]   Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells [J].
Gomperts, BN ;
Gong-Cooper, X ;
Hackett, BP .
JOURNAL OF CELL SCIENCE, 2004, 117 (08) :1329-1337
[8]   Kinesin and dynein superfamily proteins and the mechanism of organelle transport [J].
Hirokawa, N .
SCIENCE, 1998, 279 (5350) :519-526
[9]   Direct interaction of two polarity complexes implicated in epithelial tight junction assembly [J].
Hurd, TW ;
Gao, L ;
Roh, MH ;
Macara, IG ;
Margolis, B .
NATURE CELL BIOLOGY, 2003, 5 (02) :137-142
[10]   Composition and formation of intercellular junctions in epithelial cells [J].
Knust, E ;
Bossinger, O .
SCIENCE, 2002, 298 (5600) :1955-1959