Investigation of the early stages in soraphen A biosynthesis

被引:20
作者
Hill, AM [1 ]
Thompson, BL [1 ]
Harris, JP [1 ]
Segret, R [1 ]
机构
[1] Kings Coll London, Dept Chem, London WC2R 2LS, England
关键词
D O I
10.1039/b303542p
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The unusual benzoate starter unit in soraphen A derives from phenylalanine via cinnamate in a beta-oxidative (plant-like) pathway; 3-phenyl-3-hydroxypropanoate incorporates directly into soraphen by loading onto module 2 of the PKS and indirectly from the beta-oxidative pathway to generate benzoyl CoA.
引用
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页码:1358 / 1359
页数:2
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