Experimental evidence of strong anomalous diffusion in living cells

被引：126

作者：

Gal, Naama ^{[1
]}

Weihs, Daphne ^{[1
]}

机构：

[1] Technion Israel Inst Technol, Fac Biomed Engn, IL-32000 Haifa, Israel

来源：

PHYSICAL REVIEW E | 2010年 / 81卷 / 02期

关键词：

MULTIFRACTAL RANDOM-WALK; PARTICLE TRACKING; TRANSPORT; MICRORHEOLOGY; MECHANICS;

D O I：

10.1103/PhysRevE.81.020903

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

We evaluated the transport of polymeric particles internalized into living cancer cells. The mean-square displacement demonstrates superdiffusion with a scaling exponent of 1.25. Scaling exponents of a range of displacement moments are bilinear with moment order, exhibiting slopes of 0.6 and 0.8. Thus, we present experimental evidence of strong anomalous diffusion. Bilinearity indicates that particle motion is composed of subdiffusive regimes separated by active yet nonballistic flights. We discuss the results in terms of particle interactions with their microenvironment.

引用

页数：4

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