Graft selection algorithm based on congestion volume for adult living donor liver transplantation

被引:45
作者
Asakuma, M. [1 ]
Fujimoto, Y.
Bourquain, H.
Uryuhara, K.
Hayashi, M.
Tanigawa, N.
Peitgen, H.-O.
Tanaka, K.
机构
[1] Kyoto Univ, Fac Med, Dept Transplantat & Immunol, Kyoto, Japan
[2] Osaka Med Coll, Dept Gen & Gastroenterol Surg, Osaka, Japan
[3] Nagoya Univ Hosp, Dept Transplantat, Nagoya, Aichi, Japan
[4] MeVis gGmbH, Ctr Med Diagnost & Visualizat, Bremen, Germany
关键词
donor safety; graft selection; hepatic venous congestion; liver transplantation; living donor; right lobe graft;
D O I
10.1111/j.1600-6143.2007.01849.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
A major concern in adult-to-adult living donor liver transplantation is the selection of graft type; that is, is it is better to use the right lobe with or without the middle hepatic vein (MHV)? This choice has a considerable impact on donor safety, vascular reconstruction and graft function in the recipient. To facilitate making an appropriate choice, on the basis of a preliminary study (n = 17), we herein propose a graft selection algorithm using three parameters: graft-to-recipient body weight ratio (GRWR), percentage remnant liver volume (%RLV) and estimated congestion ratio (ECR). The algorithm was evaluated with 50 consecutive cases with respect to postoperative liver function of donors and recipients and survival of recipients. Postoperative recovery was comparable between the two groups (p = NS). The overall cumulative 18-month survival rate was 86.7% for the 'with MHV graft group', and 76.1% for the gwithout MHV graft grouph (p = NS). For 41 cases (82%), graft types were chosen according to the algorithm, whereas the remaining 9 cases (18%) needed detailed discussion of donor, recipient and operative factors. In conclusion, we constructed a graft selection algorithm based on congestion volume, which will contribute to objective graft-type selection in adult-to-adult LDLT.
引用
收藏
页码:1788 / 1796
页数:9
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