T-cell selection

被引：131

作者：

Jameson, SC ^{[1
]}

Bevan, MJ

机构：

[1] Univ Minnesota, Ctr Immunol, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA

[2] Univ Washington, Dept Immunol, Howard Hughes Med Inst, Seattle, WA 98195 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1998年 / 10卷 / 02期

关键词：

D O I：

10.1016/S0952-7915(98)80251-3

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Major histocompatibility complex (MHC) molecules in the thymus select from the repertoire of germline receptors those that will be most useful in mounting responses to antigen in the periphery. Recent data has shed light on the involvement of self peptides presented by the MHC in this process, and has indicated that a requirement for the constant recognition of 'self' may be essential for T-cell longevity in the periphery. (C) Current Biology Ltd ISSN 0952-7915.

引用

页码：214 / 219

页数：6

共 46 条

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