Colloidal interactions and self-assembly using DNA hybridization

被引:287
作者
Biancaniello, PL [1 ]
Kim, AJ
Crocker, JC
机构
[1] Univ Penn, Dept Phys & Astron, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Chem & Biomol Engn, Philadelphia, PA 19104 USA
关键词
D O I
10.1103/PhysRevLett.94.058302
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
The specific binding of complementary DNA strands has been suggested as an ideal method for directing the controlled self-assembly of microscopic objects. We report the first direct measurements of such DNA-induced interactions between colloidal microspheres, as well as the first colloidal crystals assembled using them. The interactions measured with our optical tweezer method can be modeled in detail by well-known statistical physics and chemistry, boding well for their application to directed self-assembly. The microspheres' binding dynamics, however, have a surprising power-law scaling that can significantly slow annealing and crystallization.
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页数:4
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