Microwave-assisted synthesis under continuous-flow conditions

被引：204

作者：

Glasnov, Toma N.

Kappe, C. Oliver

机构：

[1] Karl Franzens Univ Graz, Christian Doppler Lab Microwave Chem, A-8010 Graz, Austria

[2] Karl Franzens Univ Graz, Inst Chem, A-8010 Graz, Austria

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2007年 / 28卷 / 04期

关键词：

batch reactors; continuous flow; microwave heating; processing; synthesis; DRY-MEDIA REACTOR; ORGANIC-SYNTHESIS; SCALE-UP; COUPLING REACTIONS; SINGLE-MODE; CHEMISTRY; SUZUKI; BATCH; ACID; ESTERIFICATION;

D O I：

10.1002/marc.200600665

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Microwave-assisted chemistry is about to change the art and practice of synthesis performed in many academic and industrial laboratories. One of the major drawbacks of this enabling technology is the difficulty associated with scale-up. Because of the limited penetration depth of microwaves into absorbing media, the solution to scale-up lies in continuous-flow processing. In this review we summarize the current state of the art in this field and present an overview on published examples of microwave-assisted synthesis using continuous-flow and stop-flow processing in custom-built or commercially available microwave reactors.

引用

收藏

页码：395 / 410

页数：16

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