Stereoselective synthesis of 3-mono- and 1,3-disubstituted 4-phenyl-1,2,3,4-tetrahydroisoquinolines

被引：23

作者：

Brózda, D ^{[1
]}

Koroniak, L ^{[1
]}

Rozwadowska, MD ^{[1
]}

机构：

[1] Adam Mickiewicz Univ, Fac Chem, PL-60780 Poznan, Poland

来源：

TETRAHEDRON-ASYMMETRY | 2000年 / 11卷 / 14期

关键词：

D O I：

10.1016/S0957-4166(00)00258-5

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

(1S,2S)-(+)-Thiomicamine was transformed in high yield and with high diastereoselectivity into (3R,4R)-4-phenyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and enantiomerically pure (3R,4R)-3-hydroxymethyl-4-phenyl- and (1R,3R,4R)-3-hydroxymethyl-1-methyl-4-phenyl-1,2,3,4-tetrahydroisoquinoline derivatives. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3017 / 3025

页数：9

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