Inheritance of chronic tension-type headache investigated by complex segregation analysis

被引:21
作者
Russell, MB [1 ]
Iselius, L
Ostergaard, S
Olesen, J
机构
[1] Univ Copenhagen, Glostrup Hosp, Dept Neurol, DK-2600 Copenhagen, Denmark
[2] Karolinska Hosp, Dept Surg, S-10401 Stockholm, Sweden
关键词
D O I
10.1007/s004390050666
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
We investigated the mode of Inheritance of chronic tension-type headache in 122 families, The probands were from the Copenhagen Headache Clinic, Denmark. The criteria of the International Headache Society were used. The patterns of segregation of chronic tension-type headache were assessed by complex segregation analysis performed with the computer program POINTER. Of the 122 probands with chronic tension-type headache, 56 had 71 first-degree relatives with chronic tension-type headache. The complex segregation analysis indicates that chronic tension-type headache has multifactorial inheritance.
引用
收藏
页码:138 / 140
页数:3
相关论文
共 21 条
[11]   Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4 [J].
Ophoff, RA ;
Terwindt, GM ;
Vergouwe, MN ;
vanEijk, R ;
Oefner, PJ ;
Hoffman, SMG ;
Lamerdin, JE ;
Mohrenweiser, HW ;
Bulman, DE ;
Ferrari, M ;
Haan, J ;
Lindhout, D ;
vanOmmen, GJB ;
Hofker, MH ;
Ferrari, MD ;
Frants, RR .
CELL, 1996, 87 (03) :543-552
[12]   Comparison of first degree relatives and spouses of people with chronic tension headache [J].
Ostergaard, S ;
Russell, MB ;
Bendtsen, L ;
Olesen, J .
BMJ-BRITISH MEDICAL JOURNAL, 1997, 314 (7087) :1092-1093
[13]   IMPACT OF HEADACHE ON SICKNESS ABSENCE AND UTILIZATION OF MEDICAL-SERVICES - A DANISH POPULATION STUDY [J].
RASMUSSEN, BK ;
JENSEN, R ;
OLESEN, J .
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 1992, 46 (04) :443-446
[14]   EPIDEMIOLOGY OF HEADACHE IN A GENERAL-POPULATION - A PREVALENCE STUDY [J].
RASMUSSEN, BK ;
JENSEN, R ;
SCHROLL, M ;
OLESEN, J .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1991, 44 (11) :1147-1157
[15]   FAMILIAL OCCURRENCE OF CLUSTER HEADACHE [J].
RUSSELL, MB ;
ANDERSSON, PG ;
THOMSEN, LL .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1995, 58 (03) :341-343
[16]   INCREASED FAMILIAL RISK AND EVIDENCE OF GENETIC-FACTOR IN MIGRAINE [J].
RUSSELL, MB ;
OLESEN, J .
BRITISH MEDICAL JOURNAL, 1995, 311 (7004) :541-544
[17]   INHERITANCE OF MIGRAINE INVESTIGATED BY COMPLEX SEGREGATION ANALYSIS [J].
RUSSELL, MB ;
ISELIUS, L ;
OLESEN, J .
HUMAN GENETICS, 1995, 96 (06) :726-730
[18]   CLUSTER HEADACHE IS AN AUTOSOMAL DOMINANTLY INHERITED DISORDER IN SOME FAMILIES - A COMPLEX SEGREGATION ANALYSIS [J].
RUSSELL, MB ;
ANDERSSON, PG ;
THOMSEN, LL ;
ISELIUS, L .
JOURNAL OF MEDICAL GENETICS, 1995, 32 (12) :954-956
[19]  
RUSSELL MB, UNPUB FAMILIAL OCCUR
[20]   CEPHALIC AND EXTRACEPHALIC PRESSURE PAIN THRESHOLDS IN CHRONIC TENSION-TYPE HEADACHE [J].
SCHOENEN, J ;
BOTTIN, D ;
HARDY, F ;
GERARD, P .
PAIN, 1991, 47 (02) :145-149