A novel three-component one-pot pyrimidine synthesis based upon a coupling-isomerization sequence

被引：103

作者：

Muller, TJJ ^{[1
]}

Braun, R ^{[1
]}

Ansorge, M ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 13期

关键词：

D O I：

10.1021/ol006046e

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,4,6-Tri(hetero)aryl substituted pyrimidines can be readily synthesized in a three component one pot process based upon a coupling-isomerization sequence of an electron-poor (hetero)aryl halide and a terminal propargyl alcohol subsequently followed by a cyclocondensation with amidinium salts.

引用

页码：1967 / 1970

页数：4

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