Pertussis in Argentina and France

被引：14

作者：

Caro, Valerie

Bouchez, Valerie

Guiso, Nicole

Gatti, Blanca

Agosti, Maria Rosa

Ayala, Silvia E. Gonzalez

机构：

[1] Natl Ctr Reference Whooping Cough & Other Bordete, CNRS, FRE 2849, Inst Pasteur,Mol Prevent & Therapy Human Dis Unit, F-75724 Paris 15, France

[2] Hosp Ninos Superiora Sor Maria Ludov, Microbiol Lab, La Plata, Argentina

[3] Hosp Ninos Superiora Sor Maria Ludov, Serv Enfermedades Infecciosas, La Plata, Argentina

来源：

VACCINE | 2007年 / 25卷 / 22期

关键词：

Bordetella pertussis; pulsed-field gel electrophoresis; genotyping; Argentina; France; WHOLE-CELL VACCINE; BORDETELLA-PERTUSSIS; SEQUENCE VARIATION; EUROPEAN COUNTRIES; STRAINS; INFANTS; POLYMORPHISM; POPULATIONS; INFECTION; COVERAGE;

D O I：

10.1016/j.vaccine.2006.08.024

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We have studied the epidemiology of pertussis in two countries, Argentina and France, which have similar histories of long-term mass vaccination with a whole-cell vaccine. Both countries display a comparable epidemiology, with an increase of the incidence of the disease in non-vaccinated newborns. We used pulsed-field gel electrophoresis (PFGE) analysis and genotyping to compare Bordetella pertussis clinical isolates recovered in Argentina and France in 2001-2004. The majority of the isolates harbors prn2 allele and belongs to PFGE IV beta group. Isolates were found to be very similar genetically suggesting a common evolution of the disease in these two countries using the same vaccine. (C) 2006 Elsevier Ltd. All rights reserved.

引用

页码：4335 / 4339

页数：5

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