A tetraphenylporphyrin-peptide hybrid with high affinity for single-stranded DNA

被引:20
作者
Jain, RK [1 ]
Sarracino, DA [1 ]
Richert, C [1 ]
机构
[1] Tufts Univ, Dept Chem, Medford, MA 02155 USA
关键词
D O I
10.1039/a707803j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A tetraphenylporphyrin bearing four peptide chains, synthesized in two steps from meso-tetrakis(p-aminophenyl)porphyrin and the peptide CGKWK, binds single-stranded DNA oligomers with high affinity and inhibits degradation by nuclease S1.
引用
收藏
页码:423 / 424
页数:2
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