A comprehensive glossary of autophagy-related molecules and processes

被引:124
作者
Klionsky, Daniel J. [1 ,2 ,3 ]
Codogno, Patrice [4 ,5 ]
Cuervo, Ana Maria [6 ]
Deretic, Vojo [7 ]
Elazar, Zvulun [8 ]
Fueyo-Margareto, Juan [9 ]
Gewirtz, David A. [10 ]
Kroemer, Guido [11 ,12 ]
Levine, Beth [13 ,14 ]
Mizushima, Noboru [15 ]
Rubinsztein, David C. [16 ]
Thumm, Michael [17 ]
Tooze, Sharon A. [18 ]
机构
[1] Univ Michigan, Inst Life Sci, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Dept Mol Cellular & Dev Biol, Ann Arbor, MI 48109 USA
[3] Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA
[4] INSERM, U756, Chatenay Malabry, France
[5] Univ Paris 11, Chatenay Malabry, France
[6] Albert Einstein Coll Med, Inst Aging Res, Marion Bessin Liver Res Ctr, Dept Dev & Mol Biol, Bronx, NY 10467 USA
[7] Univ New Mexico, Hlth Sci Ctr, Dept Mol Genet & Microbiol, Albuquerque, NM 87131 USA
[8] Weizmann Inst Sci, Dept Biol Chem, IL-76100 Rehovot, Israel
[9] Univ Texas MD Anderson Canc Ctr, Dept Neurooncol, Houston, TX 77030 USA
[10] Virginia Commonwealth Univ, Massey Canc Ctr, Richmond, VA USA
[11] Inst Gustave Roussy, INSERM, U848, F-94805 Villejuif, France
[12] Univ Paris 11, Villejuif, France
[13] Univ Texas SW Med Ctr Dallas, Howard Hughes Med Inst, Dallas, TX 75390 USA
[14] Univ Texas SW Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA
[15] Tokyo Med & Dent Univ, Dept Physiol & Cell Biol, Tokyo, Japan
[16] Cambridge Inst Med Res, Dept Med Genet, Cambridge, England
[17] Univ Gottingen, Dept Biochem 2, Gottingen, Germany
[18] Canc Res UK, London Res Inst, London, England
基金
英国医学研究理事会;
关键词
autophagy; definitions; glossary; lexicon; terms; VACUOLE TARGETING PATHWAY; PROTEIN-ACTIVATING ENZYME; COILED-COIL PROTEIN; REGULATES AUTOPHAGY; PHOSPHATIDYLINOSITOL; 3-PHOSPHATE; PIECEMEAL MICROAUTOPHAGY; SACCHAROMYCES-CEREVISIAE; HEPATOCYTIC AUTOPHAGY; INTERACTING PROTEIN; VESICLE FORMATION;
D O I
10.4161/auto.6.4.12244
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Autophagy is a rapidly expanding field in the sense that our knowledge about the molecular mechanism and its connections to a wide range of physiological processes has increased substantially in the past decade. Similarly, the vocabulary associated with autophagy has grown concomitantly. This fact makes it difficult for readers, even those who work in the field, to keep up with the ever-expanding terminology associated with the various autophagy-related processes. Accordingly, we have developed a comprehensive glossary of autophagy-related terms that is meant to provide a quick reference for researchers who need a brief reminder of the regulatory effects of transcription factors or chemical agents that induce or inhibit autophagy, the function of the autophagy-related proteins, or the role of accessory machinery or structures that are associated with autophagy.
引用
收藏
页码:438 / 448
页数:11
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