Multi-ligand interactions with receptor-like protein tyrosine phosphatase β:: Implications for intercellular signaling

被引：94

作者：

Peles, E ^{[1
]}

Schlessinger, J

Grumet, M

机构：

[1] Weizmann Inst Sci, Dept Mol Cell Biol, IL-76100 Rehovot, Israel

[2] NYU Med Ctr, Dept Pharmacol, New York, NY 10016 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 04期

关键词：

D O I：

10.1016/S0968-0004(98)01195-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Receptor-like protein tyrosine phosphatase beta (RPTP beta) shows structural and functional similarity to cell adhesion molecules (CAMs). It binds to several neuronal CAMs and extracellular matrix (ECM) proteins that combine to form cell-recognition complexes. Here, the authors discuss the implications of such complexes for intercellular signaling, and the regulation of RPTP activity by cell-cell and cell-ECM contact.

引用

页码：121 / 124

页数：4

共 37 条

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