Biofilm formation by hyperpiliated mutants of Pseudomonas aeruginosa

被引：129

作者：

Chiang, P

Burrows, LL

机构：

[1] Hosp Sick Children, Ctr Infect & Biomat Res, Inst Res, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Dept Surg, Toronto, ON, Canada

来源：

JOURNAL OF BACTERIOLOGY | 2003年 / 185卷 / 07期

关键词：

D O I：

10.1128/JB.185.7.2374-2378.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Under static growth conditions, hyperpiliated, nontwitching pilT and pilU mutants of Pseudomonas aeruginosa formed dense biofilms, showing that adhesion, not twitching motility, is necessary for biofilm initiation. Under flow conditions, the pilT mutant formed mushroom-like structures larger than those of the wild type but the pilU mutant was defective in biofilm formation. Therefore, twitching motility affects the development of biofilm structure, possibly through modulation of detachment.

引用

页码：2374 / 2378

页数：5