Flow visualization as a complementary tool to hemolysis testing in the development of centrifugal blood pumps

被引：22

作者：

Yamane, T

Asztalos, B

Nishida, M

Masuzawa, T

Takiura, K

Taenaka, Y

Konishi, Y

Miyazoe, Y

Ito, K

机构：

[1] Mech Engn Lab, Biomimet Div, Tsukuba, Ibaraki 3058564, Japan

[2] Natl Cardiovasc Ctr, Osaka, Japan

[3] Nikkiso Co Ltd, Tokyo, Japan

来源：

ARTIFICIAL ORGANS | 1998年 / 22卷 / 05期

关键词：

flow visualization; rotary blood pumps; hemolysis; mechanical trauma;

D O I：

10.1046/j.1525-1594.1998.06126.x

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

With a 250% scaled-up pump model, high speed video camera, and argon ion laser light sheet, flow patterns related to hemolysis were visualized and analyzed with 4 frame particle tracking software. Different flow patterns and shear distributions were clarified by flow visualization for pumps modified to have different hemolysis levels. A combination of in vitro hemolysis tests, flow visualization, and CFD analysis suggested a close relationship between hemolysis and high sheer caused by small impeller/casing gaps. Because arbitrary cross sections can be illuminated by laser light sheet, flow visualization is a useful tool in finding locations related to hemolysis in the design process of rotary blood pumps.

引用

页码：375 / 380

页数：6

共 5 条

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BLACKSHEAR PL, 1996, ASAIO T, V12, P113

[2]

HASHIMOTO S, 1989, ARTIF ORGANS, V13, P458

[3] Computational fluid dynamic analyses to establish design process of centrifugal blood pumps [J].