Spirostanol Saponins from the Fibrous Roots of Ophiopogon japonicus (THUNB.) KER-GAWL

被引：21

作者：

Duan, Chang-Ling ^{[1
,2
]}

Li, Yu-Juan ^{[2
]}

Li, Peng ^{[2
]}

Jiang, Yong ^{[1
]}

Liu, Jian-Xun ^{[2
]}

Tu, Peng-Fei ^{[1
]}

机构：

[1] Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China

[2] China Acad Chinese Med Sci, Xiyuan Hosp, Beijing 100091, Peoples R China

来源：

HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 02期

关键词：

GLYCOSIDES; TUBER; HOMOISOFLAVONOIDS;

D O I：

10.1002/hlca.200900165

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three new steroidal saponins, (25R)-ruscogenin-3-yl alpha-L-rhamnopyranosyl-(1 -> 2)-[beta-D-xylopyranosyl-(1 -> 4)]-beta-D-glucopyranoside (1). diosgenin-3-yl 2-O-acetyl-alpha-L-rhamnopyranosyl-(1 -> 2)-[beta-D-xylopyranosyl-(1 -> 4)]-beta-D-glucopyranoside (2), and pennogenin-3-yl 2-O-acetyl-alpha-L-rhamnopyranosyl-(1 -> 2)-[beta-D-glucopyranoside-(1 -> 4)]-beta-D-glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus (THUNB.) KER-GAWL. Their structures were determined by spectroscopic methods including IR, HR-ESI-MS, and 1D- and 2D-NMR. All of these three steroidal saponins exhibited weak cytotoxicities against Hela and Hep2 cell lines.

引用

页码：227 / 232

页数：6

共 15 条

[11] RAPID COLORIMETRIC ASSAY FOR CELLULAR GROWTH AND SURVIVAL - APPLICATION TO PROLIFERATION AND CYTO-TOXICITY ASSAYS
MOSMANN, T
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1983, 65 (1-2) : 55 - 63
[12] A new C27-steroidal glycoside from Ophiopogon japonicus
Wang, Jian Zhong
Ye, Li Ming
Chen, Xiao Bing
[J]. CHINESE CHEMICAL LETTERS, 2008, 19 (01) : 82 - 84
[13] WATANABE Y, 1990, Shoyakugaku Zasshi, V44, P117
[14] WATANABE Y, 1983, CHEM PHARM BULL, V31, P3486
[15] 2 HOMOISOFLAVONES FROM OPHIOPOGON-JAPONICUS
ZHU, YX
YAN, KD
TU, GS
[J]. PHYTOCHEMISTRY, 1987, 26 (10) : 2873 - 2874

← 1 2 →