A pH responsive dendron-DNA-protein hybrid supramolecular system

被引:17
作者
Chen, Ping [1 ]
Sun, Yawei [2 ]
Liu, Huajie [2 ]
Xu, Lijin [1 ]
Fan, Qinghua [3 ]
Liu, Dongsheng [2 ]
机构
[1] Renmin Univ China, Dept Chem, Beijing 100872, Peoples R China
[2] Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Minist Educ, Beijing 100084, Peoples R China
[3] Chinese Acad Sci, Ctr Chem Biol, Inst Chem, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China
关键词
SINGLE-STRANDED-DNA; I-MOTIF; STREPTAVIDIN; DENDRIMERS; RELEASE; NANOSTRUCTURES; POLYMERS; BIND;
D O I
10.1039/c002377a
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A pH responsive dendron-DNA-protein hybrid molecular system has been designed and prepared via chemical systhesis and assembly process. The size of this molecular system could be switched by the conformation change of the i-motif DNA. Its structure and switching mechanism has been characterized by mass spectroscopy, electrophoresis, circular dichroism (CD) spectroscopy and UV/Vis spectroscopy.
引用
收藏
页码:2143 / 2145
页数:3
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