Identification and genetic diversity of two human parvovirus B19 genotype 3 subtypes

被引：59

作者：

Parsyan, Armen

Szmaragd, Camille

Allain, Jean-Pierre

Candotti, Daniel ^{[1
]}

机构：

[1] Univ Cambridge, Dept Haematol, Div Transfus Med, Cambridge, England

[2] Univ Cambridge, Dept Genet, Cambridge CB2 3EH, England

[3] Natl Blood Serv, Cambridge Blood Ctr, Cambridge, England

来源：

JOURNAL OF GENERAL VIROLOGY | 2007年 / 88卷

关键词：

D O I：

10.1099/vir.0.82496-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Three genotypes (1-3) of human parvovirus B19 have been identified. Analysis of 13 nearly full-length genotype 3 sequences from Ghana, Europe and Brazil identified two genetically distinct clusters. The classification of genotype 3 strains into two subtypes (B19/3a and B19/3b) is proposed. The rate of evolutionary change of B19 genotype 3 strains (2 x 10(-4) nucleotide substitutions per site per year) was similar to those of B19 genotype 1 and carnivore parvoviruses, supporting the hypothesis that high mutation rates are characteristic of members of the family Parvoviridae. The estimated divergence time between B19/3a and B19/3b is 525 years. In Ghana, subtype B19/3a is predominant.

引用

收藏

页码：428 / 431

页数：4

相关论文

共 19 条

[1] Characterization of parvovirus B19 genotype 2 in KU812Ep6 cells [J].

Blümel, J ;

Eis-Hübinger, AM ;

Stühler, A ;

Bönsch, C ;

Gessner, M ;

Löwer, J .

JOURNAL OF VIROLOGY, 2005, 79 (22) :14197-14206

[2] Identification and characterization of persistent human erythrovirus infection in blood donor samples [J].

Candotti, D ;

Etiz, N ;

Parsyan, A ;

Allain, JP .

JOURNAL OF VIROLOGY, 2004, 78 (22) :12169-12178

[3] Maternal-fetal transmission of human parvovirus B19 genotype 3 [J].

Candotti, Daniel ;

Danso, Kwabena ;

Parsyan, Armen ;

Dompreh, Albert ;

Allain, Jean-Pierre .

JOURNAL OF INFECTIOUS DISEASES, 2006, 194 (05) :608-611

[4] Genetic variants of parvovirus B19 identified in the United Kingdom: Implications for diagnostic testing [J].

Cohen, B. J. ;

Gandhi, J. ;

Clewley, J. P. .

JOURNAL OF CLINICAL VIROLOGY, 2006, 36 (02) :152-155

[5] B19 virus genome diversity: epidemiological and clinical correlations [J].

Gallinella, G ;

Venturoli, S ;

Manaresi, E ;

Musiani, M ;

Zerbini, M .

JOURNAL OF CLINICAL VIROLOGY, 2003, 28 (01) :1-13

[6] Prevalence of parvovirus B19 and parvovirus V9 DNA and antibodies in paired bone marrow and serum samples from healthy individuals [J].

Heegaard, ED ;

Petersen, BL ;

Heilmann, CJ ;

Hornsleth, A .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (03) :933-936

[7] Human parvovirus B19 [J].

Heegaard, ED ;

Brown, KE .

CLINICAL MICROBIOLOGY REVIEWS, 2002, 15 (03) :485-+

[8] Pathogenesis of parvovirus B19 infection: Host gene variability, and possible means and effects of virus persistence [J].

Kerr, JR .

JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH, 2005, 52 (7-8) :335-339

[9] Persistent B19 infection in immunocompetent individuals:: implications for transfusion safety [J].

Lefrère, JJ ;

Servant-Delmas, A ;

Candotti, D ;

Mariotti, M ;

Thomas, I ;

Brossard, Y ;

Lefère, F ;

Girot, R ;

Allain, JP ;

Laperche, S .

BLOOD, 2005, 106 (08) :2890-2895

[10] Evolutionary relationships among parvoviruses: Virus-host coevolution among autonomous primate parvoviruses and links between adeno-associated and avian parvoviruses [J].

Lukashov, VV ;

Goudsmit, J .

JOURNAL OF VIROLOGY, 2001, 75 (06) :2729-2740