An aggressive surgical approach is warranted in the management of cystic pancreatic neoplasms

被引：25

作者：

Hardacre, Jeffrey M. ^{[1
]}

McGee, Michael F. ^{[1
]}

Stellato, Thomas A. ^{[1
]}

Schulak, James A. ^{[1
]}

机构：

[1] Univ Hosp Cleveland, Dept Surg, Div Gen Surg, Case Med Ctr, Cleveland, OH 44106 USA

来源：

AMERICAN JOURNAL OF SURGERY | 2007年 / 193卷 / 03期

关键词：

cystic pancreatic neoplasm; serous cystic neoplasm; mucinous cystic neoplasm; intraductal papillary mucinous neoplasm;

D O I：

10.1016/j.amjsurg.2006.09.029

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background: Cystic pancreatic neoplasms encompass a range of benign to malignant disease. Recommendations for surgical management vary. Methods: Records of patients with cystic pancreatic neoplasms from January 1996 through December 2005 were retrospectively reviewed. Results: Sixty resections were performed for 16 serous cystic neoplasms, 7 mucinous cystic neoplasms (MCNs), and 37 intraductal papillary mucinous neoplasms (IPMNs). Twenty-five percent (15/60) of neoplasms contained invasive cancer. Patients with MCN or IPMN invasive neoplasms experienced significantly diminished overall 5-year survival compared to patients with IPMN carcinoma in situ neoplasms and to patients with MCN or IPMN adenoma/borderline neoplasms (22% vs. 73% vs. 94%, P = .004). Conclusions: Given the poor long-term survival of patients with cystic pancreatic neoplasms containing invasive cancer and the current difficulty to preoperatively distinguish among the various types of lesions in a reliable manner, our data support an aggressive surgical approach to the management of cystic pancreatic neoplasms. (c) 2007 Excerpta Medica Inc. All rights reserved.

引用

页码：374 / 378

页数：5