Control of nanoparticle assembly by using DNA-modified diatom templates

被引:124
作者
Rosi, NL
Thaxton, CS
Mirkin, CA
机构
[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA
[2] Northwestern Univ, Inst Nanotechnol, Evanston, IL 60208 USA
关键词
DNA; microorganism; nanostructures; self-assembly; template synthesis;
D O I
10.1002/anie.200460905
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Microorganisms point the way: The silica cell walls of various diatoms were covalently functionalized with DNA by using straightforward chemical procedures and then used as templates for the sequence-specific assembly and 3D hierarchical arrangement of prefabricated DNA-modified gold nanoparticles. The DNA was used to further direct the assembly of multiple nanoparticle layers onto the diatom templates (see picture).
引用
收藏
页码:5500 / 5503
页数:4
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