Efficacy of rapid IV administration of valproic acid for status epilepticus

被引：81

作者：

Limdi, NA

Shimpi, AV

Faught, E

Gomez, CR

Burneo, JG

机构：

[1] Univ Alabama, Sch Med, Epilepsy Ctr, Civitan Int Res Ctr, Birmingham, AL 35294 USA

[2] Brookwood Hosp, Birmingham, AL USA

[3] Univ Western Ontario, London Hlth Sci Ctr, Epilepsy Program, London, ON, Canada

来源：

NEUROLOGY | 2005年 / 64卷 / 02期

关键词：

D O I：

10.1212/01.WNL.0000149527.47600.5A

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Although not approved by the US Food and Drug Administration for the treatment of status epilepticus ( SE), valproic acid (VPA) is an emerging option for this purpose. The authors reviewed 63 patients ( 30 men) with SE treated with IV VPA (average dose, 31.5 mg/kg). Analysis of demographic, clinical, and treatment information indicated an overall efficacy of 63.3% and favorable tolerance of rapid administration.

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页码：353 / 355

页数：3

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