Sex differences in the prevalence and adverse outcomes of sarcopenia and sarcopenic obesity in community dwelling elderly in East China using the AWGS criteria

被引:160
作者
Du, Yanping [1 ,2 ,3 ]
Wang, Xiaodong [4 ]
Xie, Hua [5 ]
Zheng, Songbai [1 ,2 ,3 ]
Wu, Xiaoqing [1 ,2 ,3 ]
Zhu, Xiaoying [1 ,2 ,3 ]
Zhang, Xuemei [1 ,2 ,3 ]
Xue, Sihong [1 ,2 ,3 ]
Li, Huilin [1 ,2 ,3 ]
Hong, Wei [1 ,2 ,3 ]
Tang, Wenjing [1 ,2 ,3 ]
Chen, Minmin [1 ,2 ,3 ]
Cheng, Qun [1 ,2 ,3 ]
Sun, Jianqin [5 ]
机构
[1] Fudan Univ, Dept Osteoporosis & Bone Dis, Huadong Hosp, 221 West Yan An Rd, Shanghai 200040, Peoples R China
[2] Shanghai Geriatr Inst, Res Sect Geriatr Metab Bone Dis, Shanghai, Peoples R China
[3] Fudan Univ, Natl Clin Res Ctr Aging & Med, Shanghai, Peoples R China
[4] Zhoujiaqiao Community Hlth Serv Ctr, Shanghai, Peoples R China
[5] Fudan Univ, Huadong Hosp, Nutr Dept, 221 West Yan An Rd, Shanghai 200040, Peoples R China
基金
上海市自然科学基金;
关键词
Sarcopenia; Obesity; Sex; Prevalence; Outcome; Gender; MUSCLE MASS; BODY-COMPOSITION; FUNCTIONAL-CAPACITY; REFERENCE VALUES; OLDER-ADULTS; ASSOCIATION; MEN; DEFINITION; HEALTH; NUTRITION;
D O I
10.1186/s12902-019-0432-x
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Background Sarcopenia and sarcopenic obesity (SO) have a greater impact on the elderly. This study aimed to explore whether there were sex differences in the prevalence and adverse outcomes of sarcopenia and SO in community-dwelling elderly individuals in East China. Methods This was a cross-sectional study that enrolled 213 males and 418 females aged > 65 years. Demographic characteristics, body composition, hand grip, gait speed, and indices of glucose and lipid metabolism were collected. Sarcopenia and SO were diagnosed using the Asian Working Group for Sarcopenia criteria. Results (1) The prevalence of sarcopenia was 19.2% in males and 8.6% in females. The prevalence of SO was 7.0% in males and 2.4% in females. (2) In males, the odds ratios (ORs) of osteoporosis and dyslipidemia in the SO group were 4.21-fold and 4.15-fold higher than those in the normal group, respectively. In females, the ORs of osteoporosis and hyperglycemia in the SO group were 1.12-fold and 4.21-fold higher than those in the normal group. Conclusions Males were more likely to be sarcopenic and to have SO than females using the AWGS criteria. Females with SO were more likely to have higher blood glucose, whereas males with SO were more likely to have osteoporosis and dyslipidemia.
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页数:11
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共 44 条
[1]
A polymorphic variant of the insulin-like growth factor 1 (IGF-1) receptor correlates with male longevity in the Italian population: A genetic study and evaluation of circulating IGF-1 from the "treviso Longeva (TRELONG)" study [J].
Albani D. ;
Batelli S. ;
Polito L. ;
Vittori A. ;
Pesaresi M. ;
Gajo G.B. ;
De Angeli S. ;
Zanardo A. ;
Gallucci M. ;
Forloni G. .
BMC Geriatrics, 9 (1)
[2]
Extreme light [J].
不详 .
NATURE MATERIALS, 2016, 15 (01) :1-1
[3]
Mortality as an adverse outcome of sarcopenia [J].
Arango-Lopera, V. E. ;
Arroyo, P. ;
Gutierrez-Robledo, L. M. ;
Perez-Zepeda, M. U. ;
Cesari, M. .
JOURNAL OF NUTRITION HEALTH & AGING, 2013, 17 (03) :259-262
[4]
Baumgartner RN, 2005, PRINCIPLES PRACTICE, P909
[5]
Sarcopenic/Obesity and Physical Capacity in Older Men and Women: Data From the Nutrition as a Determinant of Successful Aging (NuAge)-the Quebec Longitudinal Study [J].
Bouchard, Danielle R. ;
Dionne, Isabelle J. ;
Brochu, Martin .
OBESITY, 2009, 17 (11) :2082-2088
[6]
Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia [J].
Chen, Liang-Kung ;
Liu, Li-Kuo ;
Woo, Jean ;
Assantachai, Prasert ;
Auyeung, Tung-Wai ;
Bahyah, Kamaruzzaman Shahrul ;
Chou, Ming-Yueh ;
Chen, Liang-Yu ;
Hsu, Pi-Shan ;
Krairit, Orapitchaya ;
Lee, Jenny S. W. ;
Lee, Wei-Ju ;
Lee, Yunhwan ;
Liang, Chih-Kuang ;
Limpawattana, Panita ;
Lin, Chu-Sheng ;
Peng, Li-Ning ;
Satake, Shosuke ;
Suzuki, Takao ;
Won, Chang Won ;
Wu, Chih-Hsing ;
Wu, Si-Nan ;
Zhang, Teimei ;
Zeng, Ping ;
Akishita, Masahiro ;
Arai, Hidenori .
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2014, 15 (02) :95-101
[7]
[陈敏 Chen Min], 2015, [中华老年医学杂志, Chinese Journal of Geriatrics], V34, P483
[8]
A cross-sectional study of loss of muscle mass corresponding to sarcopenia in healthy Chinese men and women: reference values, prevalence, and association with bone mass [J].
Cheng, Qun ;
Zhu, Xiaoying ;
Zhang, Xuemei ;
Li, Huilin ;
Du, Yanping ;
Hong, Wei ;
Xue, Sihong ;
Zhu, Hanmin .
JOURNAL OF BONE AND MINERAL METABOLISM, 2014, 32 (01) :78-88
[9]
Age and sex effects on the association between body composition and bone mineral density in healthy Chinese men and women [J].
Cheng, Qun ;
Zhu, Ying Xiao ;
Zhang, Mei Xue ;
Li, Lin Hui ;
Du, Ping Yan ;
Zhu, Min Han .
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2012, 19 (04) :448-455
[10]
Insulin resistance and sarcopenia: mechanistic links between common co-morbidities [J].
Cleasby, Mark E. ;
Jamieson, Pauline M. ;
Atherton, Philip J. .
JOURNAL OF ENDOCRINOLOGY, 2016, 229 (02) :R67-R81