High prevalence of factor V Leiden mutation in mothers of premature neonates

被引：16

作者：

Erhardt, E ^{[1
]}

Stankovics, J ^{[1
]}

Molnár, D ^{[1
]}

Adamovich, K ^{[1
]}

Melegh, B ^{[1
]}

机构：

[1] Univ Med Sch, Dept Paediat, H-7623 Pecs, Hungary

来源：

BIOLOGY OF THE NEONATE | 2000年 / 78卷 / 02期

关键词：

Leiden mutation; prematurity; intrauterine growth retardation;

D O I：

10.1159/000014263

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The prevalence of the Leiden mutation was tested in 50 mothers of premature infants and in 56 mothers of intra-uterine-growth-retarded neonates, The prevalence of the Leiden mutation was 7.2% in the mothers of growth-retarded neonates and 18% in the group of mothers of premature infants, the latter being significantly higher than the 6.3% prevalence of this mutation in healthy Hungarian subjects (p < 0.01), In spite of the relatively small number of mothers examined, the unexpected finding may call attention to a hitherto unknown relationship. Copyright (C) 2000 S. Karger AG, Basel.

引用

页码：145 / 146

页数：2

共 6 条

[1] MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].