Cholesterol homeostasis: ESCAPe from the ER

被引：12

作者：

Hampton, RY ^{[1
]}

机构：

[1] Univ Calif San Diego, Dept Biol, La Jolla, CA 92093 USA

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 08期

关键词：

D O I：

10.1016/S0960-9822(00)00434-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Transcriptional regulation and membrane traffic have traditionally been quite separate fields of biology, but they have been brought under the same roof by recent advances in understanding the cellular control of cholesterol metabolism.

引用

页码：R298 / R301

页数：4

共 21 条

[1]

Beachy PA, 1997, COLD SPRING HARB SYM, V62, P191

[2]

Brown MS, 1996, J INVEST MED, V44, P14

[3] A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood [J].

Brown, MS ;

Goldstein, JL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (20) :11041-11048

[4] Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells [J].

Burke, R ;

Nellen, D ;

Bellotto, M ;

Hafen, E ;

Senti, KA ;

Dickson, BJ ;

Basler, K .

CELL, 1999, 99 (07) :803-815

[5] Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis [J].

Carstea, ED ;

Morris, JA ;

Coleman, KG ;

Loftus, SK ;

Zhang, D ;

Cummings, C ;

Gu, J ;

Rosenfeld, MA ;

Pavan, WJ ;

Krizman, DB ;

Nagle, J ;

Polymeropoulos, MH ;

Sturley, SL ;

Ioannou, YA ;

Higgins, ME ;

Comly, M ;

Cooney, A ;

Brown, A ;

Kaneski, CR ;

BlanchetteMackie, EJ ;

Dwyer, NK ;

Neufeld, EB ;

Chang, TY ;

Liscum, L ;

Strauss, JF ;

Ohno, K ;

Zeigler, M ;

Carmi, R ;

Sokol, J ;

Markie, D ;

ONeill, RR ;

vanDiggelen, OP ;

Elleder, M ;

Patterson, MC ;

Brady, RO ;

Vanier, MT ;

Pentchev, PG ;

Tagle, DA .

SCIENCE, 1997, 277 (5323) :228-231

[6] Transport-dependent proteolysis of SREBP: Relocation of Site-1 protease from Golgi to ER obviates the need for SREBP transport to Golgi [J].

DeBose-Boyd, RA ;

Brown, MS ;

Li, WP ;

Nohturfft, A ;

Goldstein, JL ;

Espenshade, PJ .

CELL, 1999, 99 (07) :703-712

[7] REGULATION OF THE MEVALONATE PATHWAY [J].

GOLDSTEIN, JL ;

BROWN, MS .

NATURE, 1990, 343 (6257) :425-430

[8] Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein [J].

Hua, XX ;

Nohturfft, A ;

Goldstein, JL ;

Brown, MS .

CELL, 1996, 87 (03) :415-426

[9] MOLECULAR DISSECTION OF THE ROLE OF THE MEMBRANE DOMAIN IN THE REGULATED DEGRADATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE [J].

KUMAGAI, H ;

CHUN, KT ;

SIMONI, RD .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (32) :19107-19113

[10] Cholesterol: stuck in traffic [J].

Mukherjee, S ;

Maxfield, FR .

NATURE CELL BIOLOGY, 1999, 1 (02) :E37-E38

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