CD1-restricted antigen presentation: an oily matter

被引：25

作者：

Joyce, S ^{[1
]}

Van Kaer, L ^{[1
]}

机构：

[1] Vanderbilt Univ, Dept Microbiol & Immunol, Sch Med, Nashville, TN 37232 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2003年 / 15卷 / 01期

关键词：

D O I：

10.1016/S0952-7915(02)00012-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

CD1 molecules control diverse immune functions by presenting self and non-self lipid antigens to T lymphocytes. The recent solution of the human CD1 b structure has revealed the first principles for the structural basis of the presentation of unique and overlapping sets of lipids. Additionally, new studies have shed light on the unique aspects of intracellular CD1 traffic, lipid antigen processing and T cell recognition of non-peptidlic ligands.

引用

收藏

页码：95 / 104

页数：10

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