Spotlight on naturally absorbable osteofixation devices

被引:45
作者
Ashammakhi, N
Suuronen, R
Tiainen, J
Törmälä, P
Waris, T
机构
[1] Tampere Univ Technol, Inst Biomat, FIN-33101 Tampere, Finland
[2] Univ Helsinki, Dept Oral & Maxillofacial Surg, Inst Dent, FIN-00014 Helsinki, Finland
[3] Univ Helsinki, Cent Hosp, Dept Oral & Maxillofacial Surg, Helsinki, Finland
[4] Tampere Univ Hosp, Div Plast Surg, Dept Surg, Tampere, Finland
[5] Tampere Univ, FIN-33101 Tampere, Finland
关键词
bioabsorbable; biodegradable; osteofixation; self-reinforced; tissue engineering;
D O I
10.1097/00001665-200303000-00021
中图分类号
R61 [外科手术学];
学科分类号
摘要
The practice of using implants is growing day by day, and more foreign materials are being inserted for various indications. The field of implantology thus deserves intensive research and careful evaluation of results. Solutions to overcome current problems and risks are necessary. It has taken a long time to arrive at where we are now. Bioabsorbable devices were explored in the 1960s for surgical bone fixation. Failures were followed by changes in ways of thinking and innovations. Improvements in the strength properties and biocompatibility were achieved. Bioabsorbable polymeric materials such as high-molecular-weight polymers were used and also reinforced with other material or, more recently, by self-reinforcement to produce small yet strong devices. New generations of implants include those that contain bioactive substances such as antibiotics and growth factors. Developments in bioabsorbable materials continue to accommodate the new way of thinking brought about by the emergence of the field of tissue engineering. Surgeons, conversely, are also inventing new surgical techniques and methods to exploit the plastic and bioabsorbability properties of these materials for the better future of our patients. Such a multidisciplinary approach that involves surgeons and materials scientists should help to find solutions to the current limitations of these devices.
引用
收藏
页码:247 / 259
页数:13
相关论文
共 155 条
[51]  
HONIG JF, 1995, J CRANIOFAC SURG, V6, P292
[52]   SEVERE BONE-RESORPTION AND OSTEOARTHROSIS AFTER MINIPLATE FIXATION OF HIGH CONDYLAR FRACTURES - A CLINICAL AND RADIOLOGIC STUDY OF 13 PATIENTS [J].
IIZUKA, T ;
LINDQVIST, C ;
HALLIKAINEN, D ;
MIKKONEN, P ;
PAUKKU, P .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1991, 72 (04) :400-407
[53]  
ILLI OE, 1989, CHIR PEDIATR, V30, P284
[54]   Corrosion of metal orthopaedic implants [J].
Jacobs, JJ ;
Gilbert, JL ;
Urban, RM .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1998, 80A (02) :268-282
[55]  
Jukkala-Partio K, 2000, ANN CHIR GYNAECOL, V89, P45
[56]  
Jukkala-Partio K, 1998, ANN CHIR GYNAECOL FE, V87, P44
[57]   Comparison of costs in ankle fractures treated with absorbable or metallic fixation devices [J].
Juutilainen, T ;
Patiala, H ;
Ruuskanen, M ;
Rokkanen, P .
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 1997, 116 (04) :204-208
[58]  
JUUTILAINEN T, 1995, P 3 WOLRD C SURG EFF
[59]   Bioabsorbable scaffolds for guided bone regeneration and generation [J].
Kellomäki, M ;
Niiranen, H ;
Puumanen, K ;
Ashammakhi, N ;
Waris, T ;
Törmälä, P .
BIOMATERIALS, 2000, 21 (24) :2495-2505
[60]   HISTOMORPHOMETRIC EVALUATION OF STRESS SHIELDING IN MANDIBULAR CONTINUITY DEFECTS TREATED WITH RIGID FIXATION PLATES AND BONE-GRAFTS [J].
KENNADY, MC ;
TUCKER, MR ;
LESTER, GE ;
BUCKLEY, MJ .
INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 1989, 18 (03) :170-174