Protein capped nanosilver free radical oxidation: role of biomolecule capping on nanoparticle colloidal stability and protein oxidation

被引：8

作者：

Ahumada, Manuel ^{[1
,2
]}

Bohne, Cornelia ^{[3
]}

Oake, Jessy ^{[3
]}

Alarcon, Emilio, I ^{[1
,4
]}

机构：

[1] Univ Ottawa, Div Cardiac Surg Res, Heart Inst, 40 Ruskin St, Ottawa, ON, Canada

[2] Univ Mayor, Fac Ciencias, Ctr Nanotecnol Aplicada, Camino Piramide 5750, Region Metropolitana 8580745, Huechuraba, Chile

[3] Univ Victoria, Dept Chem, Victoria, BC, Canada

[4] Univ Ottawa, Fac Med, Dept Biochem Microbiol &Immunol, Ottawa, ON, Canada

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 37期

基金：

加拿大健康研究院; 加拿大自然科学与工程研究理事会;

关键词：

SILVER NANOPARTICLES; IN-VITRO; CORONA; MECHANISMS; TOXICITY;

D O I：

10.1039/c7cc08629f

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

We studied the effect of human serum albumin protein capped spherical nanosilver on the nanoparticle stability upon peroxyl radical oxidation. The nanoparticle-protein composite is less prone to oxidation compared to the individual components. However, higher concentrations of hydrogen peroxide were formed in the nanoparticle-protein system.

引用

收藏

页码：4724 / 4727

页数：4

相关论文

共 40 条

[1]

Novel specific peptides as superior surface stabilizers for silver nano structures: role of peptide chain length [J].

Ahumada, M. ;

Jacques, E. ;

Andronic, C. ;

Comer, J. ;

Poblete, H. ;

Alarcon, E. I. .

JOURNAL OF MATERIALS CHEMISTRY B, 2017, 5 (45) :8925-8928

[2]

Association models for binding of molecules to nanostructures [J].

Ahumada, Manuel ;

Lissi, Eduardo ;

Montagut, Ana Maria ;

Valenzuela-Henriquez, Francisco ;

L. Pacioni, Natalia ;

Alarcon, Emilio I. .

ANALYST, 2017, 142 (12) :2067-2089

[3]

Anomalous Hammett's plot in the quenching of Ru(bpy)32+ phosphorescence by p-substituted phenols [J].

Ahumada, Manuel ;

Lissi, Eduardo ;

Calderon, Cristian .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2016, 325 :9-12

[4]

Alarcon E., 2015, Silver Nanoparticle Applications, P1

[5]

Human serum albumin as protecting agent of silver nanoparticles: role of the protein conformation and amine groups in the nanoparticle stabilization [J].

Alarcon, Emilio I. ;

Bueno-Alejo, Carlos J. ;

Noel, Christopher W. ;

Stamplecoskie, Kevin G. ;

Pacioni, Natalia L. ;

Poblete, Horacio ;

Scaiano, J. C. .

JOURNAL OF NANOPARTICLE RESEARCH, 2013, 15 (01)

[6]

Green synthesis of silver nanoparticles and characterization of their inhibitory effects on AGEs formation using biophysical techniques [J].

Ashraf, Jalaluddin M. ;

Ansari, Mohammad Azam ;

Khan, Haris M. ;

Alzohairy, Mohammad A. ;

Choi, Inho .

SCIENTIFIC REPORTS, 2016, 6

[7]

Oxygen Toxicity and Reactive Oxygen Species: The Devil Is in the Details [J].

Auten, Richard L. ;

Davis, Jonathan M. .

PEDIATRIC RESEARCH, 2009, 66 (02) :121-127

[8]

Protein corona over silver nanoparticles triggers conformational change of proteins and drop in bactericidal potential of nanoparticles: Polyethylene glycol capping as preventive strategy [J].

Ban, Deependra Kumar ;

Paul, Subhankar .

COLLOIDS AND SURFACES B-BIOINTERFACES, 2016, 146 :577-584

[9]

A centrifugation-based physicochemical characterization method for the interaction between proteins and nanoparticles [J].

Bekdemir, Ahmet ;

Stellacci, Francesco .

NATURE COMMUNICATIONS, 2016, 7

[10]

Time Evolution of the Nanoparticle Protein Corona [J].

Casals, Eudald ;

Pfaller, Tobias ;

Duschl, Albert ;

Oostingh, Gertie Janneke ;

Puntes, Victor .

ACS NANO, 2010, 4 (07) :3623-3632

← 1 2 3 4 →