Insertion of metallated epoxynitriles into organozirconocene chlorides. A convergent synthesis of 2-cyano-1,3-dienes

被引：22

作者：

Kasatkin, AN ^{[1
]}

Whitby, RJ ^{[1
]}

机构：

[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 32期

基金：

英国工程与自然科学研究理事会;

关键词：

zirconium; carbenoid; metallated epoxides; epoxynitrile; cyanodiene;

D O I：

10.1016/S0040-4039(00)01006-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithiated epoxynitriles insert efficiently into alkenylzirconocene chlorides via a 1,2-metallate rearrangement to form intermediates which eliminate Cp2Zr(Cl)O- to afford substituted 2-cyano-1,3-dienes. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：6201 / 6205

页数：5

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