New approaches for medicinal applications of bioinorganic chemistry

被引:97
作者
Cohen, Seth M. [1 ]
机构
[1] Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
基金
美国国家科学基金会; 美国国家卫生研究院;
关键词
D O I
10.1016/j.cbpa.2007.01.012
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Inorganic and bioinorganic chemistry have made important contributions to medical science and human health in the past half century. Today, metal-containing imaging agents and therapeutics constitute a multi-billion dollar industry. Recent discoveries in bioinorganic chemistry of potential biomedical importance include the use of metal ions as synthetic scaffolds for the preparation of small molecule therapeutics, which opens up a new route to molecular structure and diversity, as well as the examination of metal-organic frameworks as biological imaging and drug delivery agents. These areas represent some of the most recent and still relatively unexplored themes in inorganic and bioinorganic chemistry that might be exciting and fruitful topics of study for the community interested in 'metals in medicine'.
引用
收藏
页码:115 / 120
页数:6
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