Tensile properties, tension-tension fatigue and biological response of polyetheretherketone-hydroxyapatite composites for load-bearing orthopedic implants

被引：303

作者：

Abu Bakar, MS

Cheng, MHW

Tang, SM

Yu, SC

Liao, K

Tan, CT

Khor, KA

Cheang, P

机构：

[1] Nanyang Technol Univ, Ctr Adv Mat Res, Sch Mech & Prod Engn, Singapore 639798, Singapore

[2] Singapore Gen Hosp, Dept Orthopaed Surg, Singapore 169608, Singapore

[3] Nanyang Technol Univ, Biomed Engn Res Ctr, Singapore 639798, Singapore

来源：

BIOMATERIALS | 2003年 / 24卷 / 13期

关键词：

hydroxyapatite; polyetheretherketone; bioactive; composites; orthopedic; implants; mechanical properties;

D O I：

10.1016/S0142-9612(03)00028-0

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Polyetheretherketone-hydroxyapatite composites were developed as alternative materials for load-bearing orthopedic applications. The amount of hydroxyapatite (HA) incorporated into the polyetheretherketone (PEEK) polymer matrix ranges from 5 to 40 vol% and these materials were successfully fabricated by injection molding. This study presents the mechanical and biological behavior of the composite materials developed. It was found that the amount of HA in the composite influenced the tensile properties. Dynamic behavior under tension-tension fatigue revealed that the fatigue-life of PEEK-HA composites were dependent on the HA content as well as the applied load. The biological responses of PEEK-HA composites carried out in vivo verified the biocompatibility and bioactive nature of the composite materials. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：2245 / 2250

页数：6

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