Colorimetric and fluorometric molecularly imprinted polymer sensors and binding assays

被引:52
作者
Stephenson, Clifton J. [1 ]
Shimizu, Ken D. [1 ]
机构
[1] Univ S Carolina, Dept Biochem & Chem, Columbia, SC 29205 USA
关键词
molecularly imprinted polymer; molecular recognition; sensor; binding assays;
D O I
10.1002/pi.2206
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
This mini review examines the utility of molecularly imprinted polymers (MIPs) in colorimetric and fluorometric sensors and binding assays. The review focuses on the challenges in developing MIP-based spectroscopic sensors. Specifically, strategies to address the low selectivities, lack of sensing mechanism and poor optical material properties of MIPs are examined and critically evaluated using examples from the literature. (C) 2007 Society of Chemical Industry.
引用
收藏
页码:482 / 488
页数:7
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