Pd(II)-Catalyzed Hydroxyl-Directed C-H Activation/C-O Cyclization: Expedient Construction of Dihydrobenzofurans

被引：311

作者：

Wang, Xisheng ^{[1
]}

Lu, Yi ^{[1
]}

Dai, Hui-Xiong ^{[1
]}

Yu, Jin-Quan ^{[1
]}

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2010年 / 132卷 / 35期

基金：

美国国家科学基金会;

关键词：

BOND FORMATION; ALIPHATIC-ALCOHOLS; ARYL HALIDES; HETEROCYCLES; AMINATION; FUNCTIONALIZATION; TEMPERATURE; ARYLATION; INDOLINES; IODIDES;

D O I：

10.1021/ja105366u

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Pd(II)-catalyzed C-H activation/C-O cyclization reaction directed by a proximate hydroxyl group has been developed. This reaction provides a new method for constructing dihydrobenzofurans, including spirocyclic analogues, a process that is potentially applicable to natural product synthesis.

引用

收藏

页码：12203 / 12205

页数：3

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