Escherichia coli O157:117 is only occasionally isolated from healthy swine, but some experimentally infected animals will shed the organism in their feces for at least 2 months. Potential explanations for the paucity of naturally occurring infections in swine, as compared to cattle, include a lack of animal-to-animal transmission so that the organism cannot be maintained within a herd, a high infectious dose, or herd management practices that prevent the maintenance of the organism in the gastrointestinal tract. We hypothesized that donor pigs infected with E. coli O157:117 would transmit the organism to naive pigs. We also determined the infectious dose and whether housing pigs individually on grated floors would decrease the magnitude or duration of fecal shedding. Infected donor pigs shedding <10(4) CFU of E. coli O157:117 per g transmitted the organism to 6 of 12 naive pigs exposed to them. The infectious dose of E. coli O157:117 for 3-month-old pigs was approximately 6 X 10(3) CFU. There was no difference in the magnitude and duration of fecal shedding by pigs housed individually on grates compared to those housed two per pen on cement floors. These results suggest that swine do not have an innate resistance to colonization by E. coli O157:H7 and that they could serve as a reservoir host under suitable conditions.
机构:
Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USAWashington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Hancock, DD
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Besser, TE
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机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Besser, TE
;
Rice, DH
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机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Rice, DH
;
Ebel, ED
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机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Ebel, ED
;
Herriott, DE
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机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Herriott, DE
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Carpenter, LV
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机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
机构:
Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USAWashington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Hancock, DD
;
Besser, TE
论文数: 0引用数: 0
h-index: 0
机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Besser, TE
;
Rice, DH
论文数: 0引用数: 0
h-index: 0
机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Rice, DH
;
Ebel, ED
论文数: 0引用数: 0
h-index: 0
机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Ebel, ED
;
Herriott, DE
论文数: 0引用数: 0
h-index: 0
机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA
Herriott, DE
;
Carpenter, LV
论文数: 0引用数: 0
h-index: 0
机构:Washington State Univ, Dept Vet Clin Sci, Field Dis Invest Unit, Pullman, WA 99164 USA