Obesity paradox in Korean patients undergoing primary percutaneous coronary intervention in ST-segment elevation myocardial infarction

被引：68

作者：

Kang, Won Yu

Jeong, Myung Ho ^{[1
]}

Ahn, Young Keun

Kim, Jong Hyun ^{[2
]}

Chae, Shung Chull ^{[3
]}

Kim, Young Jo ^{[4
]}

Hur, Seung Ho ^{[5
]}

Seong, In Whan ^{[6
]}

Hong, Taek Jong ^{[7
]}

Choi, Dong Hoon ^{[8
]}

Cho, Myeong Chan ^{[9
]}

Kim, Chong Jin ^{[10
]}

Seung, Ki Bae ^{[11
]}

Chung, Wook Sung ^{[11
]}

Jang, Yang Soo ^{[8
]}

Rha, Seung Woon ^{[12
]}

Bae, Jang Ho ^{[13
]}

Cho, Jeong Gwan

Park, Seung Jung ^{[14
]}

机构：

[1] Chonnam Natl Univ Hosp, Ctr Heart, Kwangju 501757, South Korea

[2] Busan Hanseo Hosp, Pusan, South Korea

[3] Kyungpook Natl Univ Hosp, Taegu, South Korea

[4] Yeungnom Univ Hosp, Gyongsan, South Korea

[5] Keimyung Univ Hosp, Taegu, South Korea

[6] Chungnam Natl Univ Hosp, Taejon, South Korea

[7] Pusan Natl Univ Hosp, Pusan, South Korea

[8] Yonsei Univ Hosp, Seoul, South Korea

[9] Chungbuk Natl Univ Hosp, Jinju, South Korea

[10] Kyunghee Univ Hosp, Seoul, South Korea

[11] Catholic Univ Hosp, Seoul, South Korea

[12] Univ Korea Hosp, Seoul, South Korea

[13] Konyong Univ Hosp, Seoul, South Korea

[14] Asan Med Ctr, Asan, South Korea

来源：

JOURNAL OF CARDIOLOGY | 2010年 / 55卷 / 01期

关键词：

Acute myocardial infarction; Coronary artery disease; Obesity; Prognosis; BODY-MASS INDEX; EARLY INVASIVE MANAGEMENT; LONG-TERM OUTCOMES; NATRIURETIC PEPTIDE; ARTERY-DISEASE; PRIMARY ANGIOPLASTY; ELDERLY-PATIENTS; IMPACT; MORTALITY; RISK;

D O I：

10.1016/j.jjcc.2009.10.004

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effect of body mass index (BMI) on outcomes after primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) is not well known. In patients registered in the Korean Acute Myocardial Infarction Registry (KAMIR) between November 2005 and November 2007, 3824 STEMI patients who arrived at hospital within 12 h after onset of chest pain and underwent primary PCI were analyzed, and divided into four groups according to their BMI: underweight (BMI < 18.5 kg/m(2), n = 129); normal weight (18.5 <= BMI<23.0kg/m(2), n=1253); overweight (23.0 <= BMI<27.5kg/m(2), n = 1959); and obese (BMI >= 27.5kg/m(2), n=483). In-hospital mortality, revascularization in 1 year, mortality in 1 year, and overall mortality were compared between groups. Overweight and obese group were significantly younger, had normal left ventricular ejection fraction, and were more likely to be men with a higher incidence of hypertension, diabetes, and hyperlipidemia. There were no significant differences in symptom-to-door time and door-to-balloon time between groups. Obese patients had significantly lower in-hospital and overall mortalities. Major adverse cardiac events showed a bimodal pattern. Obese STEMI patients treated with primary PCI were associated with lower mortality, which may be explained by better use of medical treatment, hemodynamic stability, and younger age. (C) 2009 Japanese College of Cardiology. Published by Elsevier Ireland Ltd. All rights reserved.

引用

页码：84 / 91

页数：8

共 25 条

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