MRI in mouse developmental biology

被引：60

作者：

Turnbull, Daniel H.

Mori, Susumu

机构：

[1] NYU, Sch Med, Skirball Inst Biomol Med, New York, NY 10016 USA

[2] NYU, Sch Med, Dept Radiol, New York, NY 10016 USA

[3] NYU, Sch Med, Dept Pathol, New York, NY 10016 USA

[4] Kennedy Krieger Inst, FM Kirby Res Ctr Funct Brain Imaging, Baltimore, MD USA

[5] Johns Hopkins Univ, Sch Med, Dept Radiol, Baltimore, MD 21205 USA

来源：

NMR IN BIOMEDICINE | 2007年 / 20卷 / 03期

关键词：

MRI; diffusion tensor imaging; brain; cardiovascular;

D O I：

10.1002/nbm.1146

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Mice are used in many studies to determine the role of genetic and molecular factors in mammalian development and human congenital diseases. MRI has emerged as a major method for analyzing mutant and transgenic phenotypes in developing mice, at both embryonic and neonatal stages. Progress in this area is reviewed, with emphasis on the use of MRI to analyze cardiovascular and neural development in mice. Comparisons are made with other imaging technologies, including optical and ultrasound imaging, discussing the potential strengths and weaknesses of MRI and identifying the future challenges for MRI in mouse developmental biology. Copyright (C) 2007 John Wiley & Sons, Ltd.

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收藏

页码：265 / 274

页数：10

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