Lihouidine, a novel spiro polycyclic aromatic alkaloid from the marine sponge Suberea n. sp (Aplysinellidae, Verongida)

被引：28

作者：

Bowden, BF ^{[1
]}

McCool, BJ

Willis, RH

机构：

[1] James Cook Univ N Queensland, Sch Pharm & Mol Sci, Dept Chem, Townsville, Qld 4811, Australia

[2] Australian Inst Marine Sci, Townsville MC, Townsville, Qld 4810, Australia

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 69卷 / 23期

关键词：

D O I：

10.1021/jo0498819

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An investigation of a new species of sponge from the genus Suberea collected at Lihou Reef in the Coral Sea afforded lihouidine, an unprecedented cytotoxic Spiro nonacyclic polyaromatic alkaloid. The structure of the alkaloid, which was racemic, was determined by a combination of ID and 2D NMR techniques and single-crystal X-ray structural analysis.

引用

页码：7791 / 7793

页数：3

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