Susceptibility loci for complex regional pain syndrome

被引：69

作者：

van de Beek, WJT

Roep, BO

van der Slik, AR

Giphart, MJ

van Hilten, BJ

机构：

[1] Leiden Univ, Ctr Med, Dept Neurol, NL-2300 RC Leiden, Netherlands

[2] Leiden Univ, Ctr Med, Dept Immunohematol & Blood Transfus, Leiden, Netherlands

来源：

PAIN | 2003年 / 103卷 / 1-2期

关键词：

complex regional pain syndrome; genetics; HLA; tonic dystonia; trauma;

D O I：

10.1016/S0304-3959(02)00444-X

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

An association between HLA-DR13 and patients with complex regional pain syndrome (CRPS) who progressed towards multifocal or generalized tonic dystonia was recently reported. We now report on a new locus, centromeric in HLA-class I, which was significantly associated with a spontaneous development of CRPS, suggesting an interaction between trauma severity and genetic factors conferring CRPS susceptibility. Additionally, an association with the D6S1014 locus was found, supporting the previous finding of an association with HLA-DR13. (C) 2003 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved.

引用

页码：93 / 97

页数：5

共 19 条

[1] Mechanisms of pain in peripheral neuropathy [J].

Attal, N ;

Bouhassira, D .

ACTA NEUROLOGICA SCANDINAVICA, 1999, 100 :12-24

[2] Complete sequence and gene map of a human major histocompatibility complex [J].

Beck, S ;

Geraghty, D ;

Inoko, H ;

Rowen, L ;

Aguado, B ;

Bahram, S ;

Campbell, RD ;

Forbes, SA ;

Guillaudeux, T ;

Hood, L ;

Horton, R ;

Janer, M ;

Jasoni, C ;

Madan, A ;

Milne, S ;

Neville, M ;

Oka, A ;

Qin, S ;

Ribas-Despuig, G ;

Rogers, J ;

Shiina, T ;

Spies, T ;

Tamiya, G ;

Tashiro, H ;

Trowsdale, J ;

Vu, Q ;

Williams, L ;

Yamazaki, M .

NATURE, 1999, 401 (6756) :921-923

[3] INDUCED TREMOR AND PARKINSONISM [J].

CARDOSO, F ;

JANKOVIC, J .

ARCHIVES OF NEUROLOGY, 1995, 52 (03) :263-270

[4] ANCESTRAL HAPLOTYPES - CONSERVED POPULATION MHC HAPLOTYPES [J].

DEGLIESPOSTI, MA ;

LEAVER, AL ;

CHRISTIANSEN, FT ;

WITT, CS ;

ABRAHAM, LJ ;

DAWKINS, RL .

HUMAN IMMUNOLOGY, 1992, 34 (04) :242-252

[5] TOUCHDOWN PCR TO CIRCUMVENT SPURIOUS PRIMING DURING GENE AMPLIFICATION [J].

DON, RH ;

COX, PT ;

WAINWRIGHT, BJ ;

BAKER, K ;

MATTICK, JS .

NUCLEIC ACIDS RESEARCH, 1991, 19 (14) :4008-4008

[6] Microsatellites in the HLA region: 1999 update [J].

Foissac, A ;

Salhi, M ;

Cambon-Thomsen, A .

TISSUE ANTIGENS, 2000, 55 (06) :477-509

[7] Human gamma-aminobutyric acid B receptor gene: Complementary DNA cloning, expression, chromosomal location, and genomic organization [J].

Goei, VL ;

Choi, J ;

Ahn, J ;

Bowlus, CL ;

Raha-Chowdhury, R ;

Gruen, JR .

BIOLOGICAL PSYCHIATRY, 1998, 44 (08) :659-666

[8] GABA (γ-amino-butyric acid) neurotransmission:: Identification and fine mapping of the human GABAB receptor gene [J].

Grifa, A ;

Totaro, A ;

Rommens, JM ;

Carella, M ;

Roetto, A ;

Borgato, L ;

Zelante, L ;

Gasparini, P .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 250 (02) :240-245

[9]

Holzer P, 1998, NEUROSCIENCE, V86, P389

[10] HLA-DQ1 associated with reflex sympathetic dystrophy [J].

Kemler, MA ;

van de Vusse, AC ;

van den Berg-Loonen, EM ;

Barendse, GAM ;

van Kleef, M ;

Weber, WEJ .

NEUROLOGY, 1999, 53 (06) :1350-1351

← 1 2 →