Silica-based nanoparticles for photodynamic therapy applications

被引：234

作者：

Couleaud, Pierre ^{[2
]}

Morosini, Vincent ^{[3
]}

Frochot, Celine ^{[2
]}

Richeter, Sebastien ^{[1
]}

Raehm, Laurence ^{[1
]}

Durand, Jean-Olivier ^{[1
]}

机构：

[1] UM2, ENSCM, UM1,Equipe Chim Mol & Org Solide, Inst Charles Gerhardt Montpellier,UMR 5253,CNRS, F-34095 Montpellier 05, France

[2] Univ Nancy 1, Lab React & Genie Procedes, UPR 3349, F-54000 Nancy, France

[3] Nancy Univ, CNRS, Ctr Alexis Vautrin, CRAN,UMR 7039, Vandoeuvre Les Nancy, France

来源：

NANOSCALE | 2010年 / 2卷 / 07期

关键词：

PHOTOSENSITIZER; CARRIER; DRUG; MECHANISMS; DELIVERY; SYSTEM;

D O I：

10.1039/c0nr00096e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Silica-based nanoparticles for applications in photodynamic therapy (PDT) have emerged as a promising field for the treatment of cancer. In this review, based on the pathway the photosensitizer is entrapped inside the silica matrix, the different methods for the synthesis of silica-based nanoparticles are described from the pioneering works to the latest achievements which concern multifunctional nanoplatforms, up-converting nanoparticles, two-photon PDT, vectorization and in vivo applications.

引用

页码：1083 / 1095

页数：13

共 40 条

[21] Mesoporous-Silica-Coated Up-Conversion Fluorescent Nanoparticles for Photodynamic Therapy [J].

Qian, Hai Sheng ;

Guo, Hui Chen ;

Ho, Paul Chi-Lui ;

Mahendran, Ratha ;

Zhang, Yong .

SMALL, 2009, 5 (20) :2285-2290

[22] Colloidal mesoporous silica nanoparticles with protoporphyrin IX encapsulated for photodynamic therapy [J].

Qian, Jun ;

Gharibi, Arash ;

He, Sailing .

JOURNAL OF BIOMEDICAL OPTICS, 2009, 14 (01)

[23] Photodynamic therapy (PDT): A short review on cellular mechanisms and cancer research applications for PDT [J].

Robertson, C. A. ;

Evans, D. Hawkins ;

Abraharnse, H. .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2009, 96 (01) :1-8

[24] Protoporphyrin IX Nanoparticle Carrier: Preparation, Optical Properties, and Singlet Oxygen Generation [J].

Rossi, Liane M. ;

Silva, Paulo R. ;

Vono, Lucas L. R. ;

Fernandes, Adjaci U. ;

Tada, Dayane B. ;

Baptista, Mauricio S. .

LANGMUIR, 2008, 24 (21) :12534-12538

[25] Ceramic-based nanoparticles entrapping water-insoluble photosensitizing anticancer drugs: A novel drug-carrier system for photodynamic therapy [J].

Roy, I ;

Ohulchanskyy, TY ;

Pudavar, HE ;

Bergey, EJ ;

Oseroff, AR ;

Morgan, J ;

Dougherty, TJ ;

Prasad, PN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (26) :7860-7865

[26] Pp IX Silica Nanoparticles Demonstrate Differential Interactions with In Vitro Tumor Cell Lines and In Vivo Mouse Models of Human Cancers [J].

Simon, Virginie ;

Devaux, Corinne ;

Darmon, Audrey ;

Donnet, Thibault ;

Thienot, Edouard ;

Germain, Matthieu ;

Honnorat, Jerome ;

Duval, Alex ;

Pottier, Agnes ;

Borghi, Elsa ;

Levy, Laurent ;

Marill, Julie .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2010, 86 (01) :213-222

[27] CONTROLLED GROWTH OF MONODISPERSE SILICA SPHERES IN MICRON SIZE RANGE [J].

STOBER, W ;

FINK, A ;

BOHN, E .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1968, 26 (01) :62-&

[28] Methylene blue-containing silica-coated magnetic particles: A potential magnetic carrier for photodynamic therapy [J].

Tada, Dayane B. ;

Vono, Lucas L. R. ;

Duarte, Evandro L. ;

Itri, Rosangela ;

Kiyohara, Pedro K. ;

Baptista, Mauricio S. ;

Rossi, Liane M. .

LANGMUIR, 2007, 23 (15) :8194-8199

[29] Photodynamic characterization and in vitro application of methylene blue-containing nanoparticle platforms [J].

Tang, W ;

Xu, H ;

Kopelman, R ;

Philbert, MA .

PHOTOCHEMISTRY AND PHOTOBIOLOGY, 2005, 81 (02) :242-249

[30] Phthalocyanines covalently bound to biomolecules for a targeted photodynamic therapy [J].

Taquet, Jean-philippe ;

Frochot, Celine ;

Manneville, Vincent ;

Barberi-Heyob, Muriel .

CURRENT MEDICINAL CHEMISTRY, 2007, 14 (15) :1673-1687

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