Role of functionalization: strategies to explore potential nano-bio applications of magnetic nanoparticles

被引：173

作者：

Bohara, Raghvendra A. ^{[1
]}

Thorat, Nanasaheb D. ^{[2
]}

Pawar, Shivaji H. ^{[1
]}

机构：

[1] DY Patil Univ, Ctr Interdisciplinary Res, Kolhapur, Maharashtra, India

[2] Univ Limerick, Dept Phys & Energy, Limerick, Ireland

来源：

RSC ADVANCES | 2016年 / 6卷 / 50期

关键词：

IRON-OXIDE NANOPARTICLES; COBALT FERRITE NANOPARTICLES; IMPROVED COLLOIDAL STABILITY; IN-SITU PREPARATION; DRUG-DELIVERY; SILICA NANOPARTICLES; FE3O4; NANOPARTICLES; SUPERPARAMAGNETIC NANOPARTICLES; BIOCOMPATIBLE SUSPENSION; BIOMEDICAL APPLICATIONS;

D O I：

10.1039/c6ra02129h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Advances in nanotechnology enable the production of magnetic nanoparticles (MNPs) with specific morphologies and the tailoring of their surfaces in order to manipulate their characteristics to suit specific applications. Magnetic nanoparticles are well-established nanomaterials that offer controlled size, biospecificity, and the ability to be manipulated externally. As a result, these nanoparticles can be explored with respect to a wider range of applications. It is essential to ensure the proper and specific functionalization of magnetic nanoparticles for their successful use in nano-bio applications. The current review focuses on the theoretical background regarding the functionalization of magnetic nanoparticles for nano-bio applications. The review covers all the important aspects regarding the functionalization of magnetic nanoparticles. The ideal requirements for their functionalization for nano-bio applications and the mechanisms behind this are explained. Different materials used in the functionalization of magnetic nanoparticles are classified and discussed in detail. The principle criteria for bioconjugation and different bioconjugation strategies are overviewed. Functionalization strategies for magnetic nanoparticles for specific bioapplications, such as magnetic hyperthermia, magnetic resonance imaging, target drug delivery, bacteria detection, enzyme immobilization, cell labelling, magnetic separation, and DNA enrichment, are highlighted.

引用

页码：43989 / 44012

页数：24

共 211 条

[1] Preparation of a biocompatible magnetic film from an aqueous ferrofluid [J].

Albornoz, Cecilia ;

Jacobo, Silvia E. .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2006, 305 (01) :12-15

[2] Ultrastable Iron Oxide Nanoparticle Colloidal Suspensions Using Dispersants with Catechol-Derived Anchor Groups [J].

Amstad, Esther ;

Gillich, Torben ;

Bilecka, Idalia ;

Textor, Marcus ;

Reimhult, Erik .

NANO LETTERS, 2009, 9 (12) :4042-4048

[3]

[Anonymous], 2013, INTRO ULTRATHIN ORGA

[4] Potential applications of enzymes immobilized on/in nano materials: A review [J].

Ansari, Shakeel Ahmed ;

Husain, Qayyum .

BIOTECHNOLOGY ADVANCES, 2012, 30 (03) :512-523

[5] Magnetic nanoparticles for drug delivery [J].

Arruebo, Manuel ;

Fernandez-Pacheco, Rodrigo ;

Ibarra, M. Ricardo ;

Santamaria, Jesus .

NANO TODAY, 2007, 2 (03) :22-32

[6] Merging High Doxorubicin Loading with Pronounced Magnetic Response and Bio-repellent Properties in Hybrid Drug Nanocarriers [J].

Bakandritsos, Aristides ;

Papagiannopoulos, Aristeidis ;

Anagnostou, Eleni N. ;

Avgoustakis, Konstantinos ;

Zboril, Radek ;

Pispas, Stergios ;

Tucek, Jiri ;

Ryukhtin, Vasyl ;

Bouropoulos, Nikolaos ;

Kolokithas-Ntoukas, Argiris ;

Steriotis, Theodore A. ;

Keiderling, Uwe ;

Winnefeld, Frank .

SMALL, 2012, 8 (15) :2381-2393

[7] A/C magnetic hyperthermia of melanoma mediated by iron(0)/iron oxide core/shell magnetic nanoparticles: a mouse study [J].

Balivada, Sivasai ;

Rachakatla, Raja Shekar ;

Wang, Hongwang ;

Samarakoon, Thilani N. ;

Dani, Raj Kumar ;

Pyle, Marla ;

Kroh, Franklin O. ;

Walker, Brandon ;

Leaym, Xiaoxuan ;

Koper, Olga B. ;

Tamura, Masaaki ;

Chikan, Viktor ;

Bossmann, Stefan H. ;

Troyer, Deryl L. .

BMC CANCER, 2010, 10

[8] Novel and efficient MR active aqueous colloidal Fe3O4 nanoassemblies [J].

Barick, K. C. ;

Aslam, M. ;

Lin, Yen-Po ;

Bahadur, D. ;

Prasad, Pottumarthi V. ;

Dravid, Vinayak P. .

JOURNAL OF MATERIALS CHEMISTRY, 2009, 19 (38) :7023-7029

[9] Nanoscale assembly of amine-functionalized colloidal iron oxide [J].

Barick, K. C. ;

Aslam, M. ;

Prasad, Pottumarthi V. ;

Dravid, Vinayak P. ;

Bahadur, Dhirendra .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2009, 321 (10) :1529-1532

[10] Magnetic particles for the separation and purification of nucleic acids [J].

Berensmeier, Sonja .

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2006, 73 (03) :495-504

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